Synthesis of hydrazone derivatives of benzofuran and their antibacterial and antifungal activity
- Authors: Subhashini N.J.1, Janaki P.1, Bhadraiah B.1
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Affiliations:
- Department of Chemistry, University College of Science
- Issue: Vol 87, No 9 (2017)
- Pages: 2021-2026
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221244
- DOI: https://doi.org/10.1134/S1070363217090183
- ID: 221244
Cite item
Abstract
A series of benzofuran hydrazones 6a–6n were synthesized from benzofuran aldehyde and substituted aromatic hydrazides 5a–5n. Structures of all compounds were confimed by IR, 1H and 13C NMR, and Mass spectral data. These compounds were evaluated for their antibacterial activity against gram-negative bacteria (Escherichia coli, –ve), gram-positive bacteria (Bacillus Subtillis, +ve), and antifungal activity against Candida albicans. All compounds demonstrated considerable activity against bacteria and fungi.
About the authors
N. J. P. Subhashini
Department of Chemistry, University College of Science
Author for correspondence.
Email: njsubhashini@yahoo.co.in
India, Hyderabad, 500007
P. Janaki
Department of Chemistry, University College of Science
Email: njsubhashini@yahoo.co.in
India, Hyderabad, 500007
B. Bhadraiah
Department of Chemistry, University College of Science
Email: njsubhashini@yahoo.co.in
India, Hyderabad, 500007