Enviar artigo por via de e-mail Synthesis and some reactions of novel (4Z)-4-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-hydrazinyl-1-phenyl-1H-imidazol-5(4H)-ones
- Autores: Khalifa N.1,2, Al-Omar M.1, Nossier E.3
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Afiliações:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Edição: Volume 87, Nº 7 (2017)
- Páginas: 1621-1626
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220885
- DOI: https://doi.org/10.1134/S1070363217070283
- ID: 220885
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Resumo
Some novel (4Z)-2-[(E)-2-arylidenehydrazinyl]-4-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-1-phenyl-1H-imidazol-5(4H)-ones have been synthesized in a one-pot threecomponent cyclocondensation of pyrazole-4-carbaldehyde derivative with glycine and different isothiocyanate derivatives. The structures of the newly synthesized compounds were characterized by analytical and spectral data.
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Sobre autores
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Autor responsável pela correspondência
Email: nagykhalifa@hotmail.com
Arábia Saudita, Riyadh, 11451; Dokki, Cairo, 12622
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Arábia Saudita, Riyadh, 11451
E. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Egito, Cairo, 11754
