Synthesis of 3-oxoesters and functional derivatives of pyrimidin-4(3 Н )-one based on 1-(2,6-dihalophenyl)cyclopropan-1-carboxylic acids

I. A. Novakov; A. S. Yablokov; M. B. Navrotskii; A. S. Mkrtchyan; A. A. Vernigora; A. S. Babushkin; V. V. Kachala; E. A. Ruchko

doi:10.1134/S1070363217020128

Synthesis of 3-oxoesters and functional derivatives of pyrimidin-4(3Н)-one based on 1-(2,6-dihalophenyl)cyclopropan-1-carboxylic acids

Авторлар: Novakov I.A.¹, Yablokov A.S.¹, Navrotskii M.B.¹, Mkrtchyan A.S.¹, Vernigora A.A.¹, Babushkin A.S.¹, Kachala V.V.², Ruchko E.A.³
Мекемелер:
1. Volgograd State Technical University
2. Zelinskii Institute of Organic Chemistry
3. Farmsintez
Шығарылым: Том 87, № 2 (2017)
Беттер: 224-230
Бөлім: Article
URL: https://journals.rcsi.science/1070-3632/article/view/218190
DOI: https://doi.org/10.1134/S1070363217020128
ID: 218190

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат
Рұқсат жабық

Рұқсат берілді
Рұқсат жабық

Тек жазылушылар үшін

Аннотация
Авторлар туралы
Әдебиет тізімі
Қосымша файлдар
Статистика

Аннотация

Special features of the synthesis and chemical transformations of novel functional derivatives of 6-[1-(2,6-dihalophenyl)cyclopropyl]pyrimidin-4(3H)-one and ethyl esters of 3-[1-(2,6-dihalophenyl)cyclopropyl]-2-methyl-3-oxopropanoic acids prepared from 2-(2,6-dihalophenyl)acetonitriles have been revealed. Novel achiral structural analogs of experimental anti-HIV agent МС-1501 have been synthesized.