Synthesis of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-diones
- Autores: Nasakin O.1, Kazantseva M.1, Gein V.2
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Afiliações:
- Chuvash State University
- Perm State Pharmaceutical Academy
- Edição: Volume 87, Nº 1 (2017)
- Páginas: 154-155
- Seção: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/218084
- DOI: https://doi.org/10.1134/S107036321701025X
- ID: 218084
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Resumo
The reaction in a mixture of 1,3-cyclohexanedione (dimedone), arylaldehyde, and ammonium acetate at 160°C during 10–15 min in the absence of solvent leads to the formation of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-diones. The structure of the products has been confirmed by IR and 1H NMR spectroscopy data. Antimicrobial activity of the obtained compounds has been studied.
Sobre autores
O. Nasakin
Chuvash State University
Email: geinvl48@mail.ru
Rússia, Cheboksary
M. Kazantseva
Chuvash State University
Email: geinvl48@mail.ru
Rússia, Cheboksary
V. Gein
Perm State Pharmaceutical Academy
Autor responsável pela correspondência
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614000