Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites
- Autores: Eryomin A.1, Pietkievich A.1, Abakshonok A.1, Siniutsich Y.1, Ignatovich Z.1, Agabekov V.1, Al-Muhanna M.2
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Afiliações:
- Institute of Chemistry of New Materials
- M.K. Al-Muhanna, King Abdulaziz City for Science and Technology (KACST)
- Edição: Volume 86, Nº 8 (2016)
- Páginas: 1886-1895
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215963
- DOI: https://doi.org/10.1134/S1070363216080181
- ID: 215963
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Resumo
Co-precipitation and ultrasonic treatment methods have been used for the in situ formation of the composites of hydroxyapatite (HA) covered with nanoparticles of magnetite as well as compositions of magnetite, gold and silver. The thioalkyl-substituted derivatives of 2-arylaminopyrimidine, structural analogs of antitumor drug Imatinib containing one or two SH groups and capable to chemisorption on hydroxyapatite and its nanocomposites, have been synthesized. Two-component Fe3O4(HA) and three-component Fe3O4(HA)Au and Fe3O4(HA)Ag composites have been found the most promising as nanocarriers of bioactive compounds.
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Sobre autores
A. Eryomin
Institute of Chemistry of New Materials
Autor responsável pela correspondência
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
A. Pietkievich
Institute of Chemistry of New Materials
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
A. Abakshonok
Institute of Chemistry of New Materials
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
Yu. Siniutsich
Institute of Chemistry of New Materials
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
Zh. Ignatovich
Institute of Chemistry of New Materials
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
V. Agabekov
Institute of Chemistry of New Materials
Email: yan47@mail.ru
Belarus, Fr. Skaryna str. 36, Minsk, BY-220141
M. Al-Muhanna
M.K. Al-Muhanna, King Abdulaziz City for Science and Technology (KACST)
Email: yan47@mail.ru
Arábia Saudita, Rhiyadh
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