Enviar artigo por via de e-mail Synthesis of new 1,3-thiazole derivatives from 2(5)-hydroxyalkyl-1,3-thiazole-5(2)-carbaldehydes
- Autores: Sinenko V.1, Slivchuk S.1, Pil’o S.1, Raenko G.2, Brovarets V.1
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Afiliações:
- Institute of Bioorganic Chemistry and Petrochemistry
- Litvinenko Institute of Physical Organic and Coal Chemistry
- Edição: Volume 86, Nº 7 (2016)
- Páginas: 1597-1603
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215650
- DOI: https://doi.org/10.1134/S1070363216070100
- ID: 215650
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Resumo
Reactions of substituted 2-hydroxyalkyl-1,3-thiazole-5-carbaldehydes and 5-hydroxyalkyl-1,3-thiazole-2-carbaldehydes with phenylhydrazine, isoniazid, N-substituted rhodanines were performed as well as Biginelli reaction with acetoacetic ester and urea. As a result, new 1,3-thiazole derivatives were obtained. They are of interest as potential bioactive substances.
Sobre autores
V. Sinenko
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ucrânia, ul. Murmanskaya 1, Kyiv, 02660
S. Slivchuk
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ucrânia, ul. Murmanskaya 1, Kyiv, 02660
S. Pil’o
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ucrânia, ul. Murmanskaya 1, Kyiv, 02660
G. Raenko
Litvinenko Institute of Physical Organic and Coal Chemistry
Email: brovarets@bpci.kiev.ua
Ucrânia, Kyiv
V. Brovarets
Institute of Bioorganic Chemistry and Petrochemistry
Autor responsável pela correspondência
Email: brovarets@bpci.kiev.ua
Ucrânia, ul. Murmanskaya 1, Kyiv, 02660
