2-Hetarylimidazoles quaternization
- Autores: El’chaninov M.1, Aleksandrov A.1, Klushin V.1
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Afiliações:
- Platov Southern Russian State Polytechnic University
- Edição: Volume 86, Nº 7 (2016)
- Páginas: 1581-1583
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215643
- DOI: https://doi.org/10.1134/S1070363216070082
- ID: 215643
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Resumo
Quaternization of 2-hetarylimidazoles by the action of methyl iodide in anhydrous benzene was performed. The reaction involving 1-methyl-2-pyridyl-1H-imidazoles was studied in detail. Relative rate of 2-hetarylimidazoles quaternization changes in parallel with their basicity. The alkylation of aza group was found to be very sensitive to steric factors. The methylation of 1-methyl-2-(3-pyridyl)-1H- and 1-methyl-2-(4- pyridyl)-1H-imidazoles was accompanied with the formation of isomeric quaternary imidazole and pyridine salts.
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Sobre autores
M. El’chaninov
Platov Southern Russian State Polytechnic University
Autor responsável pela correspondência
Email: elchaninov-43@mail.ru
Rússia, ul. Prosveshcheniya 132, Novocherkassk, 346428
A. Aleksandrov
Platov Southern Russian State Polytechnic University
Email: elchaninov-43@mail.ru
Rússia, ul. Prosveshcheniya 132, Novocherkassk, 346428
V. Klushin
Platov Southern Russian State Polytechnic University
Email: elchaninov-43@mail.ru
Rússia, ul. Prosveshcheniya 132, Novocherkassk, 346428