Synthesis and Biological Activity of New 2-{[6-Methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl]oxy}acetohydrazide Derivatives
- Авторлар: Pivazyan V.1, Ghazaryan E.1, Azaryan Z.2, Yengoyan A.1,2
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Мекемелер:
- Pesticide Synthesis and Plant Protection Research Center
- Department of General and Pharmaceutical Chemistry
- Шығарылым: Том 89, № 10 (2019)
- Беттер: 2010-2017
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223108
- DOI: https://doi.org/10.1134/S1070363219100050
- ID: 223108
Дәйексөз келтіру
Аннотация
The reaction of 6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4(3H)-one with methyl chloroacetate, followed by hydrazinolysis, gave 2-{[6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl]oxy}acetohydrazide, and the latter was used to obtain a series of new derivatives, including those containing a 1,2,4-triazole, 1,3,4-oxadiazole, or furan ring in addition to the pyrimidine fragment. Preliminary biological screening of the synthesized compounds revealed a pronounced plant growth stimulating effect at a level of 65–87% relative to heteroauxin.
Авторлар туралы
V. Pivazyan
Pesticide Synthesis and Plant Protection Research Center
Email: ayengoyan@mail.ru
Армения, Yerevan
E. Ghazaryan
Pesticide Synthesis and Plant Protection Research Center
Email: ayengoyan@mail.ru
Армения, Yerevan
Zh. Azaryan
Department of General and Pharmaceutical Chemistry
Email: ayengoyan@mail.ru
Армения, Yerevan
A. Yengoyan
Pesticide Synthesis and Plant Protection Research Center; Department of General and Pharmaceutical Chemistry
Хат алмасуға жауапты Автор.
Email: ayengoyan@mail.ru
Армения, Yerevan; Yerevan
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