Synthesis and characterization of novel pyran and pyranopyrimidines linked 8-hydroxy-7-iodoquinoline-5-sulfonamide derivatives
- Авторлар: Al-Omar M.1, Khalifa N.1,2, Amr A.1,3
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Мекемелер:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Therapeutically Chemistry Department, Pharmaceutical and Drug Industries Division
- Applied Organic Chemistry Department
- Шығарылым: Том 87, № 10 (2017)
- Беттер: 2467-2471
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221510
- DOI: https://doi.org/10.1134/S1070363217100309
- ID: 221510
Дәйексөз келтіру
Аннотация
Several novel 8-hydroxy-7-iodoquinoline-5-sulfonamides bearing pyran and pyrano[2,3-d]pyrimidine derivatives were synthesized via a one-pot base catalyzed cyclocondensation reaction of N-(4-acetylphenyl)-8-hydroxy-7-iodoquinoline-5-sulfonamide with malononitrile and arylaldehydes, followed by heterocyclization of the resulting intermediates with the appropriate reagents such as carbon disulphide, formic acid, thiourea, and formamide.
Негізгі сөздер
Авторлар туралы
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Сауд Арабиясы, Riyadh, 11451
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Therapeutically Chemistry Department, Pharmaceutical and Drug Industries Division
Хат алмасуға жауапты Автор.
Email: nagykhalifa@hotmail.com
Сауд Арабиясы, Riyadh, 11451; Dokki, Cairo, 12622
A. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Organic Chemistry Department
Email: nagykhalifa@hotmail.com
Сауд Арабиясы, Riyadh, 11451; Dokki, Cairo, 12622
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