Sonogashira reaction catalyzed by palladium isocyanide complex modified in situ
- Авторлар: Boyarskii V.1
-
Мекемелер:
- St. Petersburg State University
- Шығарылым: Том 87, № 8 (2017)
- Беттер: 1663-1666
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220935
- DOI: https://doi.org/10.1134/S1070363217080035
- ID: 220935
Дәйексөз келтіру
Аннотация
Palladium isocyanide complex modified in situ by addition of benzohydrazide as nucleophile was shown to catalyze Sonogashira reactions of phenylacetylene with iodobenzenes in refluxing ethanol in the presence of potassium carbonate. The reactions were complete in 2 h, and neither preliminary degassing nor protection from atmospheric moisture and oxygen was necessary. The yields of the cross-coupling products, unsymmetrical diarylacetylenes were only slightly lower than those obtained with the preliminarily prepared catalyst. The proposed procedure was used to synthesize a series of diarylacetylenes containing both electrondonating and electron-withdrawing substituents in the benzene rings.
Авторлар туралы
V. Boyarskii
St. Petersburg State University
Хат алмасуға жауапты Автор.
Email: v.boiarskii@spbu.ru
Ресей, Universitetskaya nab. 7–9, St. Petersburg, 199034