Мақаланы E-mail арқылы жіберу Oligonucleotide cross-linking with copper ions. Spectral and quantum chemical study
- Авторлар: Bachurin S.1, Faleeva T.2,3, Kletskii M.4, Burov O.4, Askalepova O.4, Kornienko I.3,5
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Мекемелер:
- Rostov State Medical University
- Mechnikov North–West State Medical University
- Branch no. 2, Head State Center of Forensic and Criminalistic Examinations
- Southern Federal University
- Academy of Biology and Biotechnologies
- Шығарылым: Том 86, № 12 (2016)
- Беттер: 2647-2652
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216706
- DOI: https://doi.org/10.1134/S1070363216120124
- ID: 216706
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Аннотация
Copper(II) complexes with synthetic oligonucleotides consisting of repeating adenine–thymine and guanine–cytosine complementary base pairs have been studied by UV spectroscopy and simulated by DFT quantum chemical calculations at the B3LYP/6-311G++(d,p) level of theory with inclusion of solvation (hydration) effects. The obtained data suggest selective interaction of copper(II) ions with guanine–cytosine complementary pairs, followed by DNA cross-linking at those sites.
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Авторлар туралы
S. Bachurin
Rostov State Medical University
Хат алмасуға жауапты Автор.
Email: bachurin.rostgmu@gmail.com
Ресей, per. Nakhichevanskii 29, Rostov-on-Don, 344022
T. Faleeva
Mechnikov North–West State Medical University; Branch no. 2, Head State Center of Forensic and Criminalistic Examinations
Email: bachurin.rostgmu@gmail.com
Ресей, ul. Kirochnaya 41, St. Petersburg, 191015; Lermontovskaya ul. 60, Rostov-on-Don, 344000
M. Kletskii
Southern Federal University
Email: bachurin.rostgmu@gmail.com
Ресей, ul. Bol’shaya Sadovaya 105/42, Rostov-on-Don, 344006
O. Burov
Southern Federal University
Email: bachurin.rostgmu@gmail.com
Ресей, ul. Bol’shaya Sadovaya 105/42, Rostov-on-Don, 344006
O. Askalepova
Southern Federal University
Email: bachurin.rostgmu@gmail.com
Ресей, ul. Bol’shaya Sadovaya 105/42, Rostov-on-Don, 344006
I. Kornienko
Branch no. 2, Head State Center of Forensic and Criminalistic Examinations; Academy of Biology and Biotechnologies
Email: bachurin.rostgmu@gmail.com
Ресей, Lermontovskaya ul. 60, Rostov-on-Don, 344000; pr. Stachki, 194/1, Rostov-on-Don, 344090
