Мақаланы E-mail арқылы жіберу A novel method for the synthesis of maxacalcitol
- Авторлар: Song W.1, Wang Y.1, Liu D.1, Fang W.1, Lu Q.1
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Мекемелер:
- Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
- Шығарылым: Том 86, № 1 (2016)
- Беттер: 173-177
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/213569
- DOI: https://doi.org/10.1134/S1070363216010278
- ID: 213569
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Аннотация
Maxacalcitol (1), a kind of active vitamin D drugs, was prepared from pregnenolone acetate (2) using a novel synthetic method including the combination of five-step organic transformations and one-step biological transformation. The new protocol was shorter, milder, and simpler than the reported approaches. The unoptimized overall yield was 0.178%. The structure of all intermediates and final product was confirmed by 1H NMR, 13C NMR and MS techniques.
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Авторлар туралы
W.-Q. Song
Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
Email: luqun112@126.com
ҚХР, Chengdu, 610031
Y.-H. Wang
Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
Email: luqun112@126.com
ҚХР, Chengdu, 610031
D.-N. Liu
Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
Email: luqun112@126.com
ҚХР, Chengdu, 610031
W.-Z. Fang
Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
Email: luqun112@126.com
ҚХР, Chengdu, 610031
Q. Lu
Laboratory of Synthesis and Catalysis, School of Life Sciences and Engineering
Хат алмасуға жауапты Автор.
Email: luqun112@126.com
ҚХР, Chengdu, 610031
