Synthesis and Structure of 4-Het(aryl)-3,5,5-trimethoxycarbonyl-2-pyrrolidones


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Abstract

Condensation of 2-het(aryl)-1,1-dimethoxycarbonylethenes with acetylaminomalonic acid ester afforded (3R*,4S*)-4-(4-methoxyphenyl)-, (3R*,4S*)-4-(3,4-methylenedioxyphenyl)-, (3R*,4S*)-4-(4-dimethylaminophenyl)-, (3R*,4S*)-4-(2-furyl)-, (3R*,4S*)-4-(indol-3-yl)-, (3R*,4S*)-4-(1-methylindol-3-yl)-, and (3R*,4S*)-4-(1-benzylindol-3-yl)-3,5,5-tris(methoxycarbonyl)-2-pyrrolidones.

About the authors

N. V. Gorodnicheva

Herzen State Pedagogical University of Russia

Email: kohrgpu@yandex.ru
Russian Federation, nab. r. Moiki 48, St. Petersburg, 191186

E. S. Ostroglyadov

Herzen State Pedagogical University of Russia

Email: kohrgpu@yandex.ru
Russian Federation, nab. r. Moiki 48, St. Petersburg, 191186

O. S. Vasil’yeva

Herzen State Pedagogical University of Russia

Email: kohrgpu@yandex.ru
Russian Federation, nab. r. Moiki 48, St. Petersburg, 191186

S. V. Makarenko

Herzen State Pedagogical University of Russia

Author for correspondence.
Email: kohrgpu@yandex.ru
Russian Federation, nab. r. Moiki 48, St. Petersburg, 191186


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