Synthesis and Antibacterial Evaluation of Benzofuran Based 3,5-Disubstituted Isoxazoles


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Abstract

A series of novel benzofuran-isoxazole 7a–7j hybrid heterocyclic molecules are synthesized. The structures of compounds 7a–7j are assessed by IR, NMR, MASS spectroscopy and elemental analysis. The target compounds 7a–7j are screened for their antibacterial activity and demonstrated excellent to moderate activity against gram-positive and gram-negative bacteria.

About the authors

V. Sunitha

Department of Chemistry, University College of Science

Email: pochampalli.ou.chemi@gmail.com
India, Saifabad, Hyderabad, Telangana, 500004

A. Kishore Kumar

Department of Humanities and Sciences

Email: pochampalli.ou.chemi@gmail.com
India, Shamshabad, Hyderabad, Telangana, 501218

Ch. Abraham Lincoln

Department of Chemistry, University College of Science

Email: pochampalli.ou.chemi@gmail.com
India, Hyderabad, Telangana, 500007

P. Jalapathi

Department of Chemistry, University College of Science

Author for correspondence.
Email: pochampalli.ou.chemi@gmail.com
India, Hyderabad, Telangana, 500007

V. Gopal Reddy

Department of Chemistry, University College of Science

Email: pochampalli.ou.chemi@gmail.com
India, Saifabad, Hyderabad, Telangana, 500004


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