Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts
- Authors: Tatarinov D.A.1,2, Terekhova N.V.1,2, Voloshina A.D.1, Sapunova A.S.1, Lyubina A.P.1,2, Mironov V.F.1,2
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Affiliations:
- Arbuzov Institute of Organic and Physical Chemistry
- Kazan (Volga Region) Federal University
- Issue: Vol 88, No 9 (2018)
- Pages: 1800-1805
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222402
- DOI: https://doi.org/10.1134/S1070363218090062
- ID: 222402
Cite item
Abstract
New dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium salts bearing various substituents at the phosphorus atom were synthesized. Antimicrobial activity of the salts obtained was estimated. Derivatives with 2-methoxyphenyl substituents at the phosphorus atom are most active against grampositive bacteria. Herewith, dibenzyl-substituted phosphonium derivatives possess the best antifungal activity.
About the authors
D. A. Tatarinov
Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University
Author for correspondence.
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan
N. V. Terekhova
Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan
A. D. Voloshina
Arbuzov Institute of Organic and Physical Chemistry
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
A. S. Sapunova
Arbuzov Institute of Organic and Physical Chemistry
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
A. P. Lyubina
Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan
V. F. Mironov
Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan