Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts


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Abstract

New dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium salts bearing various substituents at the phosphorus atom were synthesized. Antimicrobial activity of the salts obtained was estimated. Derivatives with 2-methoxyphenyl substituents at the phosphorus atom are most active against grampositive bacteria. Herewith, dibenzyl-substituted phosphonium derivatives possess the best antifungal activity.

About the authors

D. A. Tatarinov

Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University

Author for correspondence.
Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan

N. V. Terekhova

Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University

Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan

A. D. Voloshina

Arbuzov Institute of Organic and Physical Chemistry

Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

A. S. Sapunova

Arbuzov Institute of Organic and Physical Chemistry

Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

A. P. Lyubina

Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University

Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan

V. F. Mironov

Arbuzov Institute of Organic and Physical Chemistry; Kazan (Volga Region) Federal University

Email: datint@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan


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