The First 1-Hydroxypropylidenebisphosphonic Acid with 1,8-Naphthyridinone Substituent: Synthesis and Structure
- Authors: Bodrin G.V.1, Pasechnik M.P.1, Matveeva A.G.1, Aysin R.R.1, Matveev S.V.1, Goryunov E.I.1, Strelkova T.V.1, Brel V.K.1
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Affiliations:
- Nesmeyanov Institute of Organoelement Compounds
- Issue: Vol 88, No 9 (2018)
- Pages: 1792-1799
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222401
- DOI: https://doi.org/10.1134/S1070363218090050
- ID: 222401
Cite item
Abstract
1-Hydroxy-3-(5,7-dimethyl-2-oxo-1,2-dihydro-1,8-naphthyridin-1-yl)propylidenebisphosphonic acid has been synthesized. The structure of the acid and its precursors synthesized for the first time, 3-(5,7-dimethyl-2-oxo-1,2-dihydro-1,8-naphthyridin-1-yl)propionic acid and the corresponding methyl ester, in the solid state and in the DMSO solution has been elucidated by means of vibrational (IR and Raman) and multinuclear (1H, 13C, and 31P) NMR spectroscopy.
About the authors
G. V. Bodrin
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
M. P. Pasechnik
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
A. G. Matveeva
Nesmeyanov Institute of Organoelement Compounds
Author for correspondence.
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
R. R. Aysin
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
S. V. Matveev
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
E. I. Goryunov
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
T. V. Strelkova
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991
V. K. Brel
Nesmeyanov Institute of Organoelement Compounds
Email: phoc@ineos.ac.ru
Russian Federation, ul. Vavilova 28, Moscow, 119991