Synthesis of New Tetrazole Derivatives and Their Biological Evaluation
- Authors: Soliman H.A.1, Kalmouch A.2, Awad H.M.3, Abdel Wahed N.A.4
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Affiliations:
- Photochemistry Department
- Peptide Chemistry Department
- Tanning Materials and Leather Technology Department
- Chemistry of Natural and Microbial Products Department
- Issue: Vol 88, No 8 (2018)
- Pages: 1726-1733
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222381
- DOI: https://doi.org/10.1134/S1070363218080273
- ID: 222381
Cite item
Abstract
An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out.
About the authors
H. A. Soliman
Photochemistry Department
Author for correspondence.
Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622
A. Kalmouch
Peptide Chemistry Department
Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622
H. M. Awad
Tanning Materials and Leather Technology Department
Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622
N. A. M. Abdel Wahed
Chemistry of Natural and Microbial Products Department
Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622