Microwave Assisted Synthesis and Antimicrobial Activity of ( E )-1-{2/3/4-[(1-Aryl-1 H -1,2,3-triazol-4-yl)methoxy]phenyl}-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones

Vijay Kumar Pujari; Srilalitha Vinnakota; Ramana Kumar Kakarla; Sreedhar Maroju; Arram Ganesh; S. Pervaram

doi:10.1134/S1070363218070241

Microwave Assisted Synthesis and Antimicrobial Activity of (E)-1-{2/3/4-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones

Authors: Pujari V.K.¹, Vinnakota S.², Kakarla R.K.³, Maroju S.¹, Ganesh A.³, Pervaram S.³
Affiliations:
1. New Age Life Science Pvt Ltd., Mallapur
2. Department of Chemistry, Faculty of Science and Technology
3. Department of Chemistry
Issue: Vol 88, No 7 (2018)
Pages: 1502-1507
Section: Article
URL: https://journals.rcsi.science/1070-3632/article/view/222333
DOI: https://doi.org/10.1134/S1070363218070241
ID: 222333

Cite item

Full Text

Open Access
Restricted Access

Access granted
Restricted Access

Subscription Access

Abstract
About the authors
References
Statistics

Abstract

A novel series of (E)-1-{2/3/4-[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones is synthesised from terminal alkynes with aromatic azides by the Click reaction in the presence of copper sulphate and sodium ascorbate in DMF: water under microwave irradiation. All the synthesised compounds are characterised by IR, ¹H and ¹³C NMR, and mass spectra, and tested in vitro for antimicrobial activity.