An Efficient Synthesis of (R or S)-4-Methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol


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Abstract

Based on thilation by the Lawesson’s reagent (LR), a concise and efficient synthesis of (R or S)-4-methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol was developed with relatively high yield.

About the authors

Guang Huang

School of Pharmacy; Shanghai Institute of Pharmaceutical Industry

Email: qqmeng@sjtu.edu.cn
China, Shanghai, 200240; Shanghai, 201203

Hui-ran Zhao

School of Pharmaceutical Sciences and Chemistry

Email: qqmeng@sjtu.edu.cn
China, Dali, 671000

Wen Zhou

School of Pharmacy

Email: qqmeng@sjtu.edu.cn
China, Shanghai, 200240

Qing-qing Meng

School of Pharmacy

Author for correspondence.
Email: ssli@sjtu.edu.cn
China, Shanghai, 200240

Qi-jing Zhang

School of Pharmacy

Email: qqmeng@sjtu.edu.cn
China, Shanghai, 200240

Jin-yun Dong

School of Pharmacy

Email: qqmeng@sjtu.edu.cn
China, Shanghai, 200240

Bao-quan Zhu

Shanghai Institute of Pharmaceutical Industry

Email: qqmeng@sjtu.edu.cn
China, Shanghai, 201203

Shao-shun Li

School of Pharmacy

Author for correspondence.
Email: qqmeng@sjtu.edu.cn
China, Shanghai, 200240


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