Microwave assisted one-pot synthesis of linear and angular furo chromanone scaffolds and their in vitro antimicrobial activity
- Authors: Venkataramana R.1, Ramana Reddy C.V.2, Ashok D.2, Nagaraju N.3
-
Affiliations:
- Sebond Science
- Department of Chemistry
- Department of Microbiology
- Issue: Vol 87, No 4 (2017)
- Pages: 850-856
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219484
- DOI: https://doi.org/10.1134/S1070363217040302
- ID: 219484
Cite item
Abstract
A new series of linear and angular alkyl substituted furochromanone derivatives have been synthesized in one pot microwave irradiation assisted process from ortho-hydroxy acetyl (linear and angular) benzofurans and aliphatic aldehydes in the presence of pyrrolidine. Various alkyl substituted furochromanones were synthesized with high yields. The in vitro antimicrobial activity of the products was tested. The structures of the compound have been elucidated on the basis of elemental analysis, IR, 1H and 13C NMR, and MS spectral data.
About the authors
R. Venkataramana
Sebond Science
Email: vrr9@yahoo.com
India, Nacharam, Hyderabad, Telangana, 500076
Ch. Venkata Ramana Reddy
Department of Chemistry
Author for correspondence.
Email: vrr9@yahoo.com
India, Hyderabad, Telangana, 500085
D. Ashok
Department of Chemistry
Email: vrr9@yahoo.com
India, Hyderabad, Telangana, 500007
N. Nagaraju
Department of Microbiology
Email: vrr9@yahoo.com
India, Hyderabad, Telangana, 500007