Email this article Alkylation of 4-(phenylthio)-1H-pyrazol-5-ols with methyl bromoacetate
- Authors: Vydzhak R.N.1, Panchishin S.Y.1, Brovarets V.S.1
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Affiliations:
- Institute of Bioorganic Chemistry and Petrochemistry
- Issue: Vol 87, No 2 (2017)
- Pages: 231-238
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218205
- DOI: https://doi.org/10.1134/S107036321702013X
- ID: 218205
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Abstract
Alkylation of 4-(phenylthio)-1H-pyrazol-5-ols with methyl bromoacetate has afforded a series of phenyl pyrazolyl sulfides which have been oxidized into sulfones. The resulting esters have been hydrolyzed into the corresponding acids. The synthesized compounds potentially exhibit biological activity.
About the authors
R. N. Vydzhak
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
S. Ya. Panchishin
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
V. S. Brovarets
Institute of Bioorganic Chemistry and Petrochemistry
Author for correspondence.
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
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