Synthesis and properties of 4-phosphorylated derivatives of 5-hydroxyalkylamino-1,3-oxazoles
- Authors: Abdurakhmanova E.R.1, Lukashuk E.I.1, Golovchenko A.V.1, Brovarets V.S.1
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Affiliations:
- Institute of Bioorganic Chemistry and Petrochemistry
- Issue: Vol 86, No 7 (2016)
- Pages: 1584-1596
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215646
- DOI: https://doi.org/10.1134/S1070363216070094
- ID: 215646
Cite item
Abstract
Reactions of derivatives of diethyl 1-acylamino-2,2,2-trichloroethylphosphonates with different pharmacophore aminoalkanols afforded new 5-hydroxyalkylamino-1,3-oxazole derivatives. The latter are promising substrates for producing new 4-phosphorylated peptidomimetics containing alcohol residues.
About the authors
E. R. Abdurakhmanova
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
E. I. Lukashuk
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
A. V. Golovchenko
Institute of Bioorganic Chemistry and Petrochemistry
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660
V. S. Brovarets
Institute of Bioorganic Chemistry and Petrochemistry
Author for correspondence.
Email: brovarets@bpci.kiev.ua
Ukraine, ul. Murmanskaya 1, Kyiv, 02660