Synthesis, characterization, and antibacterial activity of some thiazoles derived from allyl thioureas
- Authors: Khare R.1, Sharma J.1, Sharma A.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 86, No 3 (2016)
- Pages: 702-707
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/214434
- DOI: https://doi.org/10.1134/S1070363216030312
- ID: 214434
Cite item
Abstract
Synthesis of thiazoles was carried out from allyl thioureas using different cyclizing agents such as hydrogen chloride gas and bromine. Synthesized compounds were characterized by IR, 1H and 13C NMR, mass spectrometry, and elemental analysis. The synthesized thiazoles were evaluated for their antibacterial activity against Gram postitive (Lactobacillus bulgaris and Streptococcus mitis) and Gram negative (Yersinia) as well as antifungal activity against Aspergillus niger fungi.
Keywords
About the authors
R. Khare
Department of Chemistry
Author for correspondence.
Email: drrajshreekhare@gmail.com
India, Haryana, 133207
J. Sharma
Department of Chemistry
Email: drrajshreekhare@gmail.com
India, Haryana, 133207
A. Sharma
Department of Chemistry
Email: drrajshreekhare@gmail.com
India, Haryana, 133207