Synthesis, characterization, and antibacterial activity of some thiazoles derived from allyl thioureas


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Abstract

Synthesis of thiazoles was carried out from allyl thioureas using different cyclizing agents such as hydrogen chloride gas and bromine. Synthesized compounds were characterized by IR, 1H and 13C NMR, mass spectrometry, and elemental analysis. The synthesized thiazoles were evaluated for their antibacterial activity against Gram postitive (Lactobacillus bulgaris and Streptococcus mitis) and Gram negative (Yersinia) as well as antifungal activity against Aspergillus niger fungi.

About the authors

R. Khare

Department of Chemistry

Author for correspondence.
Email: drrajshreekhare@gmail.com
India, Haryana, 133207

J. Sharma

Department of Chemistry

Email: drrajshreekhare@gmail.com
India, Haryana, 133207

A. Sharma

Department of Chemistry

Email: drrajshreekhare@gmail.com
India, Haryana, 133207


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