Synthesis of Alkylphosphoryl-Containing 4(5)-Arylimidazolin-2-ones


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Abstract

The acid-catalyzed reaction of {2-[1-(2,2-dimethoxyethyl)-3-(phenylcarboxamido)]ethyl}phosphonate or diethyl [2-(2-oxo-3-phenyl-2,3-dihydro-1H-imidazol-1-yl)ethyl]phosphonate with resorcinol and its derivatives afforded new 4(5)-arylimidazolin-2-ones. The ratio of the resulting regioisomers is significantly affected by the structure of the starting compounds, which allows one to obtain products with a predominance of one regioisomer.

About the authors

A. V. Smolobochkin

A.E. Arbuzov Institute of Organic and Physical Chemistry of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Author for correspondence.
Email: smolobochkin@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

A. S. Gazizov

A.E. Arbuzov Institute of Organic and Physical Chemistry of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: smolobochkin@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

K. V. Matylitskii

Kazan National Research Technological University

Email: smolobochkin@iopc.ru
Russian Federation, Kazan, Tatarstan

L. I. Vagapova

A.E. Arbuzov Institute of Organic and Physical Chemistry of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: smolobochkin@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

A. R. Burilov

A.E. Arbuzov Institute of Organic and Physical Chemistry of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University

Email: smolobochkin@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088; Kazan, Tatarstan

M. A. Pudovik

A.E. Arbuzov Institute of Organic and Physical Chemistry of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”

Email: smolobochkin@iopc.ru
Russian Federation, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088

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