Email this article Synthesis and Biological Activity of N-Aryl(alkyl)-2-[2-(9H-fluoren-9-ylidene)hydrazinylidene]-5,5-dimethyl-4-oxohexanamides
- Authors: Siutkina A.I.1, Igidov N.M.1, Dmitriev M.V.2, Makhmudov R.R.2,3, Novikova V.V.1
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Affiliations:
- Ministry of Health Protection of the Russian Federation
- Perm State National Research University
- Federal Research Center for Medical and Preventive Health Risk Management Technologies
- Issue: Vol 89, No 7 (2019)
- Pages: 1388-1393
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222982
- DOI: https://doi.org/10.1134/S1070363219070065
- ID: 222982
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Abstract
Ring opening of 5-tert-butyl-3-[(9H-fluoren-9-ylidene)hydrazinylidene]furan-2(3H)-one by the action of primary amines afforded a series of new 2-[(9H-fluoren-9-ylidene)hydrazinylidene]-5,5-dimethyl-4-oxohexan-amides. The synthesized compounds were tested for antinociceptive and antimicrobial activities.
About the authors
A. I. Siutkina
Ministry of Health Protection of the Russian Federation
Author for correspondence.
Email: syutkina.alyona@yandex.ru
Russian Federation, Perm
N. M. Igidov
Ministry of Health Protection of the Russian Federation
Email: syutkina.alyona@yandex.ru
Russian Federation, Perm
M. V. Dmitriev
Perm State National Research University
Email: syutkina.alyona@yandex.ru
Russian Federation, Perm
R. R. Makhmudov
Perm State National Research University; Federal Research Center for Medical and Preventive Health Risk Management Technologies
Email: syutkina.alyona@yandex.ru
Russian Federation, Perm; Perm
V. V. Novikova
Ministry of Health Protection of the Russian Federation
Email: syutkina.alyona@yandex.ru
Russian Federation, Perm
