Synthesis and Antimicrobial Activity of 3-{2-[(1-Aryl-1 H -1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles

K. Santhosh Kumar; S. Mohanty; G. P. Reddy; V. Siddaiah; J. D. Lilakar; G. L. Goud

doi:10.1134/S1070363219060197

Synthesis and Antimicrobial Activity of 3-{2-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles

Authors: Kumar K.S.¹^,2, Mohanty S.¹, Reddy G.P.¹, Siddaiah V.², Lilakar J.D.³, Goud G.L.⁴
Affiliations:
1. Process Research and Development
2. Department of Organic Chemistry and FDW
3. PI Industries Limited
4. Spectrum Biosciences
Issue: Vol 89, No 6 (2019)
Pages: 1221-1224
Section: Article
URL: https://journals.rcsi.science/1070-3632/article/view/222951
DOI: https://doi.org/10.1134/S1070363219060197
ID: 222951

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Abstract

A novel series 3-{2-[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles derivatives is synthesized from 1-(5-fluoro-2-hydroxyphenyl)ethanone. All the synthesized compounds are characterized by IR, ¹H and ¹³C NMR, and mass spectral data, and tested for their in vitro antimicrobial activity against bacterial and fungal organisms.