Email this article Synthesis and Biological Activity of Arylcyclopentane-1-carboxylic Acids Aminoesters
- Authors: Aghekyan A.A.1, Mkryan G.G.1, Tsatinyan A.S.1, Gasparyan G.V.1
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Affiliations:
- A.L. Mnjoyan Institute of Fine Organic Chemistry
- Issue: Vol 89, No 5 (2019)
- Pages: 1051-1054
- Section: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/222922
- DOI: https://doi.org/10.1134/S107036321905027X
- ID: 222922
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Abstract
1-Arylcyclopentane-1-carboxylic acids were synthesized by alkaline hydrolysis of the corresponding nitriles. Reactions of the acid chlorides with N,N-dialkylaminoalkyl-and hetarylalkylalkanols provided new aminoester derivatives of 1-arylcyclopentane-1-carboxylic acids. Sympatholytic and adrenolytic activity of the obtained amino esters hydrochlorides was studied.
About the authors
A. A. Aghekyan
A.L. Mnjoyan Institute of Fine Organic Chemistry
Author for correspondence.
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
G. G. Mkryan
A.L. Mnjoyan Institute of Fine Organic Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
A. S. Tsatinyan
A.L. Mnjoyan Institute of Fine Organic Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
G. V. Gasparyan
A.L. Mnjoyan Institute of Fine Organic Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
