Email this article Synthesis and Antimicrobial Activity of 1-Aryl-4-(arylimino)-6-iminohexahydro-1,3,5-triazine-2-thione Derivatives
- Authors: Siva Sankara Babu T.1, Srinivasu N.1, Saha B.2, Venkat Reddy S.2
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Affiliations:
- Division of Chemistry, Department of Science and Humanities, Vignan’s Foundation for Science
- NACL Industries Limited (R&D Center)
- Issue: Vol 89, No 4 (2019)
- Pages: 824-830
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222881
- DOI: https://doi.org/10.1134/S1070363219040303
- ID: 222881
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Abstract
A series of 6-imino-1-aryl-4-(arylimino)-1,3,5-triazinane-2-thione derivatives are synthesized by cyclization of 1-aryl-3-cyanoguanidine with aryl isothiocyante in the presence of sodium methoxide under MW irradiation. Structures of the synthesized compounds 3a-j are elucidated from 1H and 13C NMR, MS, and IR, data. The synthesized compounds are evaluated for their antimicrobial activity against B. subtilis, S. aureus, P. aeruginosa, and E. Coli. Some compounds demonstrate promising activity against the tested strains.
About the authors
T. Siva Sankara Babu
Division of Chemistry, Department of Science and Humanities, Vignan’s Foundation for Science
Email: navulurisrinivasu@gmail.com
India, Guntur
N. Srinivasu
Division of Chemistry, Department of Science and Humanities, Vignan’s Foundation for Science
Author for correspondence.
Email: navulurisrinivasu@gmail.com
India, Guntur
B. Saha
NACL Industries Limited (R&D Center)
Email: navulurisrinivasu@gmail.com
India, Hyderabad
S. Venkat Reddy
NACL Industries Limited (R&D Center)
Email: navulurisrinivasu@gmail.com
India, Hyderabad
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