Supramolecular Complexes of 3-Epi-2-deoxyecdysone with Cyclodextrins and Their Anti-Inflammatory Activity


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Abstract

The ecdysteroid 3-epi-2-deoxyecdysone has been isolated from the aerial part of Acanthophyllum gypsophiloides Regel. The complexes formation of the ecdysteroid with α-, β-, λ-, and 2-hydroxypropyl-β-cyclodextrins has been studied by means of NMR spectroscopy. Anti-inflammatory activity of the obtained 3-epi-2-deoxyecdysone complexes with cyclodextrins has been investigated.

About the authors

B. S. Temirgaziev

International Scientific and Production Holding “Phytochemistry”; E. A. Buketov Karaganda State University

Author for correspondence.
Email: b_a_h_a1990@mail.ru
Kazakhstan, ul. Gazalieva 4, Karaganda, 100009; Karaganda

B. I. Tuleuov

International Scientific and Production Holding “Phytochemistry”

Email: b_a_h_a1990@mail.ru
Kazakhstan, ul. Gazalieva 4, Karaganda, 100009

M. A. Romanova

International Scientific and Production Holding “Phytochemistry”

Email: b_a_h_a1990@mail.ru
Kazakhstan, ul. Gazalieva 4, Karaganda, 100009

R. B. Seidakhmetova

International Scientific and Production Holding “Phytochemistry”

Email: b_a_h_a1990@mail.ru
Kazakhstan, ul. Gazalieva 4, Karaganda, 100009

T. M. Seilkhanov

Sh. Ualikhanov Kokshetau State University

Email: b_a_h_a1990@mail.ru
Kazakhstan, Kokshetau

O. T. Seilkhanov

Sh. Ualikhanov Kokshetau State University

Email: b_a_h_a1990@mail.ru
Kazakhstan, Kokshetau

L. K. Salkeeva

E. A. Buketov Karaganda State University

Email: b_a_h_a1990@mail.ru
Kazakhstan, Karaganda

S. M. Adekenov

International Scientific and Production Holding “Phytochemistry”

Email: b_a_h_a1990@mail.ru
Kazakhstan, ul. Gazalieva 4, Karaganda, 100009


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