Supramolecular Complexes of 3-Epi-2-deoxyecdysone with Cyclodextrins and Their Anti-Inflammatory Activity

B. S. Temirgaziev; B. I. Tuleuov; M. A. Romanova; R. B. Seidakhmetova; T. M. Seilkhanov; O. T. Seilkhanov; L. K. Salkeeva; S. M. Adekenov

doi:10.1134/S1070363219030095

Supramolecular Complexes of 3-Epi-2-deoxyecdysone with Cyclodextrins and Their Anti-Inflammatory Activity

Authors: Temirgaziev B.S.¹^,2, Tuleuov B.I.¹, Romanova M.A.¹, Seidakhmetova R.B.¹, Seilkhanov T.M.³, Seilkhanov O.T.³, Salkeeva L.K.², Adekenov S.M.¹
Affiliations:
1. International Scientific and Production Holding “Phytochemistry”
2. E. A. Buketov Karaganda State University
3. Sh. Ualikhanov Kokshetau State University
Issue: Vol 89, No 3 (2019)
Pages: 424-428
Section: Article
URL: https://journals.rcsi.science/1070-3632/article/view/222784
DOI: https://doi.org/10.1134/S1070363219030095
ID: 222784

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Abstract

The ecdysteroid 3-epi-2-deoxyecdysone has been isolated from the aerial part of Acanthophyllum gypsophiloides Regel. The complexes formation of the ecdysteroid with α-, β-, λ-, and 2-hydroxypropyl-β-cyclodextrins has been studied by means of NMR spectroscopy. Anti-inflammatory activity of the obtained 3-epi-2-deoxyecdysone complexes with cyclodextrins has been investigated.