Email this article Synthesis and Molecular Docking Studies of Novel 5-Arylideneaminouracils
- Authors: Koz G.1
-
Affiliations:
- Department of Chemistry
- Issue: Vol 89, No 1 (2019)
- Pages: 122-127
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222718
- DOI: https://doi.org/10.1134/S1070363219010225
- ID: 222718
Cite item
Open Access
Access granted
Subscription Access
Abstract
A series of novel 5-arylideneaminouracils is synthesized from 5-aminouracil and substituted salicylaldehydes, and characterized by spectroscopic methods. DNA interactions of model molecules are explored using molecular docking simulations that reveal that these types of molecules can act as DNA groove binders.
Keywords
About the authors
G. Koz
Department of Chemistry
Author for correspondence.
Email: gamzedkoz@gmail.com
Turkey, Bursa, 16190
