Synthesis of 2-Amino-5-hydroxy-5-phosphonovaleric Acid
- Authors: Ragulin V.V.1
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Affiliations:
- Institute of Physiologically Active Substances of the Russian Academy of Sciences
- Issue: Vol 88, No 9 (2018)
- Pages: 1915-1917
- Section: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/222430
- DOI: https://doi.org/10.1134/S1070363218090256
- ID: 222430
Cite item
Abstract
The synthesis of a new analog of 2-amino-5-phosphonovaleric acid (AP5), namely 2-amino-5-hydroxy-5-phosphonovaleric acid, by successive Michael addition of acetamidomalonic ester to acrolein and Abramov’s phosphorylation of the aldehydes formed in situ was developed.
About the authors
V. V. Ragulin
Institute of Physiologically Active Substances of the Russian Academy of Sciences
Author for correspondence.
Email: rvalery@dio.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
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