Synthesis of Macrocyclic Stereoisomers Substituted with Oligolactide Fragments
- Authors: Gorbachuk V.V.1, Padnya P.L.1, Stoikov I.I.1
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Affiliations:
- Butlerov Institute of Chemistry
- Issue: Vol 88, No 9 (2018)
- Pages: 1838-1841
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222410
- DOI: https://doi.org/10.1134/S1070363218090128
- ID: 222410
Cite item
Abstract
Acylation of cone and 1,3-alternate stereoisomers of hydrazides of p-tert-butylthaicalix[4]arene tetrasubstituted at the lower rim with S,S-lactide in dimethylsulfoxide has afforded the macrocyclic oligolactide derivatives containing 16 (cone) to 24 (1,3-alternate) lactide fragments. It has been shown that nanosized aggregates (80 nm) are formed with silver nitrate in the case of the cone stereoisomer containing the oligolactide fragments at one side of the macrocyclic rim, whereas submicron particles (400 nm) are formed in the case of the 1,3-alternate conformation when the substituents are at different sides of the macrocycle.
About the authors
V. V. Gorbachuk
Butlerov Institute of Chemistry
Email: ivan.stoikov@mail.ru
Russian Federation, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
P. L. Padnya
Butlerov Institute of Chemistry
Email: ivan.stoikov@mail.ru
Russian Federation, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
I. I. Stoikov
Butlerov Institute of Chemistry
Author for correspondence.
Email: ivan.stoikov@mail.ru
Russian Federation, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
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