New Possibilities of the Kabachnik–Fields and Pudovik Reactions in the Phthalocyanine-Catalyzed Syntheses of α-Aminophosphonic and α-Aminophosphinic Acid Derivatives
- Authors: Shuvalov M.V.1, Maklakova S.Y.1, Rudakova E.V.2, Kovaleva N.V.2, Makhaeva G.F.2, Podrugina T.A.1,2
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Affiliations:
- Faculty of Chemistry
- Institute of Physiologically Active Compounds
- Issue: Vol 88, No 9 (2018)
- Pages: 1761-1775
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222396
- DOI: https://doi.org/10.1134/S1070363218090013
- ID: 222396
Cite item
Abstract
The results of systematic studies demonstrated wide possibilities of the three-component Kabachnik–Fields and two-component Pudovik reactions catalyzed by metal phthalocyanines in the synthesis of structurally diverse α-aminophosphonates. Extension of this catalytic method to the synthesis α-aminophosphinates gave rise to a series of α-amino- and α-hydrazinophosphinates based on biogenic amino acids. A number of α-hydrazinophosphonates showed a good antioxidant activity.
About the authors
M. V. Shuvalov
Faculty of Chemistry
Email: podrugina@mail.ru
Russian Federation, Moscow, 119991
S. Yu. Maklakova
Faculty of Chemistry
Email: podrugina@mail.ru
Russian Federation, Moscow, 119991
E. V. Rudakova
Institute of Physiologically Active Compounds
Email: podrugina@mail.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
N. V. Kovaleva
Institute of Physiologically Active Compounds
Email: podrugina@mail.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
G. F. Makhaeva
Institute of Physiologically Active Compounds
Email: podrugina@mail.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
T. A. Podrugina
Faculty of Chemistry; Institute of Physiologically Active Compounds
Author for correspondence.
Email: podrugina@mail.ru
Russian Federation, Moscow, 119991; Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
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