Synthesis and Antibacterial Evaluation of Benzofuran Based Di-1,2,3-triazoles

Abstract

A series of novel benzofuran-1,2,3-triazole hybrid molecules are synthesized using the click chemistry approach. Structures of the synthesized compounds were assessed by IR, NMR, and mass spectroscopy. The tests of final products 10a–10l for their antibacterial activity demonstrate excellent to good activity against gram-positive and gram-negative bacteria.