Synthesis, Structures, and Molecular Docking of Some Bioactive Benzamide Derivatives as Ionic Solids

Аннотация

Five new substituted benzamide derivatives as ionic solids are prepared and characterized by FT-IR, ¹H, and ¹³C NMR spectroscopy. The crystal structure for compound 2 is determined by X-ray crystallography. The compounds are bio-assayed for their bactericidal, fungicidal, anti-oxidant, and urease inhibition activities. The molecular docking results accumulated for the compounds correlate with their biological activity and reveal high binding affinity towards jack bean urease.