Email this article Synthesis, Structures, and Molecular Docking of Some Bioactive Benzamide Derivatives as Ionic Solids
- Authors: Raheel A.1, Imtiaz-ud-Din 1, Taj M.B.1, Tahir M.N.2, Al-Shakban M.1
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Affiliations:
- Department of Chemistry
- Department of Physics
- Issue: Vol 88, No 7 (2018)
- Pages: 1508-1514
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222335
- DOI: https://doi.org/10.1134/S1070363218070253
- ID: 222335
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Abstract
Five new substituted benzamide derivatives as ionic solids are prepared and characterized by FT-IR, 1H, and 13C NMR spectroscopy. The crystal structure for compound 2 is determined by X-ray crystallography. The compounds are bio-assayed for their bactericidal, fungicidal, anti-oxidant, and urease inhibition activities. The molecular docking results accumulated for the compounds correlate with their biological activity and reveal high binding affinity towards jack bean urease.
About the authors
A. Raheel
Department of Chemistry
Email: drimtiazuddin@yahoo.com
Pakistan, Islamabad, 45320
Imtiaz-ud-Din
Department of Chemistry
Author for correspondence.
Email: drimtiazuddin@yahoo.com
Pakistan, Islamabad, 45320
M. B. Taj
Department of Chemistry
Email: drimtiazuddin@yahoo.com
Pakistan, Islamabad, 45320
M. N. Tahir
Department of Physics
Email: drimtiazuddin@yahoo.com
Pakistan, Sargodha, 40100
M. Al-Shakban
Department of Chemistry
Email: drimtiazuddin@yahoo.com
United Kingdom, Manchester, M13 9PL
