Synthesis and Structure of 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides

Аннотация

1-Alkoxycarbonylmethyl-4-heteryl-2-pyrrolidones were synthesized by alkylation of 4-heteryl-2-pyrrolidones. 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides were prepared through the reaction of N-esters with ammonia. The resulting acetamides of 2-pyrrolidones exhibit nootropic properties, antiarrhythmic and antiischemic activity.