Synthesis of 1-[2-(1 H -Indol-3-yl)ethyl]-4-acetyl-3-hydroxy-5-phenyl-1 H -pyrrol-2(5 H )-ones

O. E. Nasakin; M. I. Kazantseva; L. I. Varkentin; V. L. Gein

doi:10.1134/S1070363218060373

Synthesis of 1-[2-(1H-Indol-3-yl)ethyl]-4-acetyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones

Authors: Nasakin O.E.¹, Kazantseva M.I.¹, Varkentin L.I.², Gein V.L.²
Affiliations:
1. Ulyanov Chuvash State University
2. Perm State Pharmaceutical Academy
Issue: Vol 88, No 6 (2018)
Pages: 1270-1272
Section: Letters to the Editor
URL: https://journals.rcsi.science/1070-3632/article/view/222278
DOI: https://doi.org/10.1134/S1070363218060373
ID: 222278

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Abstract
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Abstract

1-[2-(1H-indol-3-yl)ethyl]-4-acetyl-3-hydroxy-5-phenyl-1H-pyrrole-2(5H)-ones were synthesized by the short heating of a mixture of tryptamine, aromatic aldehyde, and methyl acetylpyruvate followed by stirring at room temperature for one day.

Keywords

N,N-tryptamine heterocyclic analogues, 1-[2-(1H-indol-3-yl)ethyl]-4-acetyl-3-hydroxy-5-phenyl-1H-pyrrole-2(5H)-ones

About the authors

O. E. Nasakin

Ulyanov Chuvash State University

Email: geinvl48@mail.ru
Russian Federation, Cheboksary

M. I. Kazantseva

Ulyanov Chuvash State University

Email: geinvl48@mail.ru
Russian Federation, Cheboksary

L. I. Varkentin

Perm State Pharmaceutical Academy

Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990

V. L. Gein