Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates


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Abstract

Pyrido[2,3-d]pyrimidine derivatives were synthesized by the reaction of 2-hydrazinopyrido[2,3-d]-pyrimidin-4(3H)-one with different aryl aldehydes and active methylene compounds. Their structures were characterized by spectroscopic methods.

About the authors

N. M. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy; Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division

Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Cairo, Dokki, 12622

E. S. Nossier

Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)

Email: nagykhalifa@hotmail.com
Egypt, Cairo, 11754

A. E. Amr

Applied Organic Chemistry Department

Email: nagykhalifa@hotmail.com
Egypt, Cairo, Dokki, 12622


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