Email this article Phosphorus-Containing Aminocarboxylic Acids: XV. α,ω-Diamino-ω,ω-diphosphonoalkylcarboxylic Acids
- Authors: Ragulin V.V.1
-
Affiliations:
- Institute of Physiologically Active Substances of the Russian Academy of Sciences
- Issue: Vol 88, No 5 (2018)
- Pages: 1045-1048
- Section: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/222219
- DOI: https://doi.org/10.1134/S1070363218050341
- ID: 222219
Cite item
Open Access
Access granted
Subscription Access
Abstract
A general method for the synthesis of phosphonic aminocarboxylic acids combining aminodiphosphonic and amino acid functions in one molecule was developed. Amino acids of a new type are AP-acids analogs, which are ligands of glutamate receptors that determine the processes of information transmission and processing in the central nervous system, and can also be promising compounds as new components of radiopharmaceuticals.
About the authors
V. V. Ragulin
Institute of Physiologically Active Substances of the Russian Academy of Sciences
Author for correspondence.
Email: rvalery@dio.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
