Mixed Ligand Complexes Derived from Semicarbazone Schiff Base and Heterocyclic Ligands: Structure and Antimicrobial Activity

Abstract

A series of M(II) ternary complexes [M(L)Phen] and [M(L)Oxine], where M = Co(II), Ni(II), Cu(II), and Zn(II), L = ((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide, Phen = 1,10-phenanthroline and Oxine = 8-hydroxy chloroquinoline, were synthesized and characterized by UV-Vis, ESR, IR, mass spectra, and TG-DTA data. Morphology and crystallinity of the complex [Ni(L)Phen] were studied by scanning electron microscopy. The crystal systems of Cu(II) complexes were determined by powder X-ray diffraction. Biological activity of the ligand and its metal complexes has been screened against four bacterial strains.