Synthesis and Structure ( Z )- N -Aryl-2-hydroxy-4-oxo-4-phenylbut-2-enamides

V. L. Gein; T. M. Zamaraeva; E. V. Gorgopina; N. M. Igidov; O. V. Bobrovskaya; M. V. Dmitriev

doi:10.1134/S1070363218040321

Synthesis and Structure (Z)-N-Aryl-2-hydroxy-4-oxo-4-phenylbut-2-enamides

Authors: Gein V.L.¹, Zamaraeva T.M.¹, Gorgopina E.V.¹, Igidov N.M.¹, Bobrovskaya O.V.¹, Dmitriev M.V.²
Affiliations:
1. Perm State Pharmaceutical Academy
2. Perm State National Research University
Issue: Vol 88, No 4 (2018)
Pages: 832-835
Section: Letters to the Editor
URL: https://journals.rcsi.science/1070-3632/article/view/222160
DOI: https://doi.org/10.1134/S1070363218040321
ID: 222160

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Abstract

Reactions of 5-phenyl-2,3-dihydrofuran-2,3-dione with aromatic amines in anhydrous dioxane or methyl benzoylpyruvate with aromatic amines in the presence of sodium acetate in glacial acetic acid afforded (Z)-N-aryl-2-hydroxy-4-oxo-4-phenylbut-2-enamides.