Email this article Synthesis and Antimicrobial Activity of (Z)-3-{[3-Oxobenzofuran-2(3H)-ylidene]methyl}-4H-chromen-4-one Derivatives
- Authors: Pervaram S.1, Ashok D.2, Reddy C.V.1, Sarasija M.1, Rao B.A.2
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Affiliations:
- Department of Chemistry
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Issue: Vol 88, No 3 (2018)
- Pages: 566-572
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222090
- DOI: https://doi.org/10.1134/S1070363218030283
- ID: 222090
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Abstract
A series of (Z)-3-{[3-oxobenzofuran-2(3H)-ylidene]methyl}-4H-chromen-4-one derivatives have been synthesized from 2-hydroxyl acetophenones by the Vilesmeier–Haack reaction, Claisen–Schmidt reaction and mercury(II) acetate/cupric bromide. All the synthesized compounds were characterized by IR, 1H and 13C NMR, and mass spectral data and elemental analysis. The products were tested for their in vitro antimicrobial activity.
About the authors
S. Pervaram
Department of Chemistry
Email: Sridhar.pervaram@gmail.com
India, Hyderabad, Telangana, 500085
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Author for correspondence.
Email: Sridhar.pervaram@gmail.com
India, Hyderabad, Telangana, 500007
C. V. R. Reddy
Department of Chemistry
Email: Sridhar.pervaram@gmail.com
India, Hyderabad, Telangana, 500085
M. Sarasija
Department of Chemistry
Email: Sridhar.pervaram@gmail.com
India, Karimnagar, Telangana, 505001
B. A. Rao
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: Sridhar.pervaram@gmail.com
India, Hyderabad, Telangana, 500007
