Facile One Pot Multi-Component Solvent-Free Synthesis of 2,4,5-Trisubstituted Imidazoles Using “Green” and Expeditious Ionic Liquid Catalyst under Microwave Irradiation


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Abstract

Acetic acid functionalized poly(4-vinylpyridinium) bromide is a highly efficient and recyclable catalyst for the construction of 2,4,5-trisubstituted imidazole derivatives by a three-component condensation of benzyl with various aldehydes and ammonium acetate under solvent free conditions. The microwave initiated process leads to analytically pure compounds within 2–5 min. The advantages of this “green” methodology are cost-effectiveness, simple procedure, low energy consumption, no involvement of organic solvents, safe operation, clean reaction profile, high yields, and recyclability of the catalyst.

About the authors

B. Sonyanaik

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

K. Ashok

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

S. Rambabu

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

D. Ravi

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

A. Kurumanna

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

P. Madhu

Department of Chemistry

Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

B. Sakram

Department of Chemistry

Author for correspondence.
Email: bschemou@gmail.com
India, Telangana, Hyderabad, 500007

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