Email this article Enantioselective Bioreduction of Acetophenone into (R)- and (S)-1-Phenylethanols
- Authors: Chanysheva A.R.1, Vorobyova E.N.1, Zorin V.V.1
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Affiliations:
- Ufa State Petroleum Technological University
- Issue: Vol 87, No 13 (2017)
- Pages: 3259-3262
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221921
- DOI: https://doi.org/10.1134/S1070363217130229
- ID: 221921
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Abstract
The possibility of enantioselective bioreduction of acetophenone into (R)- and (S)-1-phenylethanol used in the synthesis of antifeedant, antidiabetic, antidepressant, antirabic, antiparasitic, antimicrobial, and antifungal agents is investigated. The influence of various exogenous reducing agents (isopropanol, ethanol, and glucose) on the yields of the target products and the enantioselectivity of the bioreduction of acetophenone is studied.
About the authors
A. R. Chanysheva
Ufa State Petroleum Technological University
Author for correspondence.
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
E. N. Vorobyova
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
V. V. Zorin
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
