Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-2-alkyloxy-6-substituted pyridine-3-carbonitriles


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Abstract

A group of new 2-alkyloxypyridine-3-carbonitriles linked pyrenyl-pyrazole functions has been obtained via reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different methyl aryl ketones. The newly compounds were assured by spectroscopic and elemental analysis.

About the authors

N. M. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy; Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division

Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622

M. A. Al-Omar

Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy

Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451

M. M. Taha

Department of Chemistry, Faculty of Science

Email: nagykhalifa@hotmail.com
Egypt, Menoufia


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