Email this article Synthesis and characterization of novel chalcones linked 3-[1-(3-chlorophenyl)-3-(pyren-1-yl)]-1H-pyrazole moiety
- Authors: Khalifa N.M.1,2, Al-Omar M.A.1, Ali O.M.1,3
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Affiliations:
- Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
- Therapeutical Chemistry Department, Pharmaceutical, and Drug Industries Division
- Department of Chemistry, Faculty of Medical and Applied Science
- Issue: Vol 87, No 11 (2017)
- Pages: 2699-2702
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221629
- DOI: https://doi.org/10.1134/S1070363217110275
- ID: 221629
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Abstract
New series of pyrenyl–pyrazole based chalcones have been synthesized and characterized via the condensation of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different substituted acetophenones in alkaline media. Structures of the newly synthesized compounds were elucidated from spectroscopic and elemental analysis data.
About the authors
N. M. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Therapeutical Chemistry Department, Pharmaceutical, and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
M. A. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
O. M. Ali
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Department of Chemistry, Faculty of Medical and Applied Science
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Taif
