One-pot three-component green synthesis of novel dihydrophthalazine-1,4-diones
- 作者: Suman M.1, Vijayabhaskar B.2, Syam Kumar U.K.3, Venkateswara Rao B.4
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隶属关系:
- Process Research & Development
- GVK Bio sciences PVT LTD
- Integrated Product Development, Innovation Plaza
- Department of Organic Chemistry, Foods, Drugs, and Water
- 期: 卷 87, 编号 9 (2017)
- 页面: 2039-2044
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221257
- DOI: https://doi.org/10.1134/S1070363217090201
- ID: 221257
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详细
Green and efficient one-pot three-component synthesis of novel 2-(7-amino-2,2-dimethyl-4-oxo-5-phenyl-4,5-dihydropyrano[2,3-d][1,3]dioxin-6-ylcarbonyl)-2,3-dihydrophthalazine-1,4-diones have been developed by condensing 3-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-2-yl)-3-oxopropanenitrile with benzaldehydes and Meldrum’s acid using L-proline as catalyst in ethanol at room temperature. The products have been isolated as pure compounds in good yields without using column chromatography.
作者简介
M. Suman
Process Research & Development
编辑信件的主要联系方式.
Email: sumandrreddysandra@gmail.com
印度, Srikakulam District, Pydibhimavaram, Ranasthalam Mandal, 532409
B. Vijayabhaskar
GVK Bio sciences PVT LTD
Email: sumandrreddysandra@gmail.com
印度, Survay no. 125 (part), 126, IDA, Mallapur, Hyderabad, 500076
U. Syam Kumar
Integrated Product Development, Innovation Plaza
Email: sumandrreddysandra@gmail.com
印度, R. R. Dist., Bachupalli, Qutubullapur, Andhra Pradesh, 500072
B. Venkateswara Rao
Department of Organic Chemistry, Foods, Drugs, and Water
Email: sumandrreddysandra@gmail.com
印度, Visakhapatnam, 530003
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