Synthesis and some transformations of 2-(4-isopropyl-2-methyl-2-ethyltetrahydro-2 H -pyran-4-yl)ethanamine

N. S. Arutyunyan; R. L. Nazaryan; L. A. Akopyan; N. Z. Akopyan; G. A. Panosyan; G. A. Gevorgyan

doi:10.1134/S1070363217070313

Synthesis and some transformations of 2-(4-isopropyl-2-methyl-2-ethyltetrahydro-2H-pyran-4-yl)ethanamine

Authors: Arutyunyan N.S.¹, Nazaryan R.L.¹, Akopyan L.A.¹, Akopyan N.Z.¹, Panosyan G.A.², Gevorgyan G.A.¹
Affiliations:
1. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry
2. Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Issue: Vol 87, No 7 (2017)
Pages: 1634-1637
Section: Letters to the Editor
URL: https://journals.rcsi.science/1070-3632/article/view/220906
DOI: https://doi.org/10.1134/S1070363217070313
ID: 220906

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Abstract

Condensation of 2-(4-isopropyl-2-methyl-2-ethyltetrahydro-2H-pyran-4-yl)ethanamine with aromatic aldehydes and ketones and subsequent reduction of the azomethines formed gave secondary amines of the tetrahydropyran series. Reaction of the latter with acetic acid and propionic acid chlorides provided the corresponding amides.